Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging with "Minimally-Invasive Segmental Artery Coil-Embolization": A Randomized Controlled Multicentre Trial
Start Date: 01/01/2017
Duration: 60 months
Area: New therapies for chronic diseases
“Through the innovative treatment being tested by PAPAartis, the body is stimulated to create a robust alternative blood supply to the spinal cord before the aneurysm repair is carried out, probably reducing the risk of paralysis.”
PAPAartis is a research project jointly funded by the EU and the German Research Foundation (DFG) to carry out a clinical trial of an exciting new advance in the treatment of aortic aneurysms.
The PAPAartis project is the largest publicly funded RCT in aortic aneurysm in the world and aims to collect data to solve the most devastating complication in aortic surgery since the first repair of an aortic aneurysm more than 60 years ago.
The objective of the project is to reduce the risk of spinal cord injury associated with open and endovascular treatment techniques currently used in patients with thoracoabdominal aortic aneurysms. Spinal cord injury during aneurysm repair most likely arises from an interrupted and/or reduced blood supply to the spinal cord.